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Compound InformationSONAR Target prediction
Name:

Prochlorperazine dimaleate

Unique Identifier:LOPAC 00300
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C28ClH32N3O8S
Molecular Weight:573.834 g/mol
X log p:16.724  (online calculus)
Lipinksi Failures1
TPSA35.02
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:4
Canonical Smiles:CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1.OC(=O)C=CC(O)=O.OC(=O)C=CC(O)=O
Class:Dopamine
Action:Antagonist

Found: 1 active | as graph: single | with analogs
Species: 4932
Condition: WHI5
Replicates: 2
Raw OD Value: r im 0.4169±0.040093
Normalized OD Score: sc h 0.6516±0.0550338
Z-Score: -10.6336±2.93069
p-Value: 5.57934e-18
Z-Factor: -0.352503
Fitness Defect: 39.7275
Bioactivity Statement: Active
Experimental Conditions
Library:Lopac
Plate Number and Position:13|H5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-04-20 YYYY-MM-DD
Plate CH Control (+):0.046475±0.00089
Plate DMSO Control (-):0.660975±0.05638
Plate Z-Factor:0.7296
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DBLink | Rows returned: 6
66010 but-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
5281032 but-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
5462338 but-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
5462695 2-chloro-10-[3-(4-methyl-2,3,5,6-tetrahydropyrazin-1-yl)propyl]phenothiazine;
(E)-4-hydroxy-4-oxo-but-2-enoate
6436057 but-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
6537213 but-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine

internal high similarity DBLink | Rows returned: 0

active | Cluster 6041 | Additional Members: 22 | Rows returned: 151 2 3 Next >> 
LAT002B04 0.5375
SPE01500575 0.5375
Prest437 0.5375
LOPAC 00320 0.5375
Prest1278 0.5
SPE01503936 0.452054794520548

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